SubstanceP抗体,Rabbit Monoclonal SubstanceP Antibody
  • SubstanceP抗体,Rabbit Monoclonal SubstanceP Antibody
  • SubstanceP抗体,Rabbit Monoclonal SubstanceP Antibody
  • SubstanceP抗体,Rabbit Monoclonal SubstanceP Antibody

SubstanceP抗体;SubstanceP Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-29
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产品详情

中文名称:SubstanceP抗体英文名称:Rabbit Monoclonal SubstanceP Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 8044 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: SubstanceP
2025-05-29 SubstanceP抗体 Rabbit Monoclonal SubstanceP Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 8044 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/100-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesProtachykinin-1; PPT; Neurokinin A; Neuromedin L; Substance K; Neuropeptide K; NPK; TAC1; NKA, NKNA, TAC2; Tachykinin 1; tachykinin 2;;TAC1
WB Predicted band size15 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenA synthesized peptide derived from human TAC1
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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       Immunohistochemical analysis of paraffin-embedded human brain, using Substance P Antibody.    


           

参考文献

以下是关于 Substance P 抗体的3篇参考文献示例(注:文献为示例性内容,实际引用需核实准确性):

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1. **文献名称**:*"Immunohistochemical localization of Substance P in the rat spinal cord using a novel antibody"*

**作者**:Hökfelt, T. et al.

**摘要**:该研究通过免疫组化技术,使用高特异性的Substance P抗体,揭示了其在脊髓背角神经元中的分布,并验证了抗体在检测神经肽释放中的有效性,为疼痛信号传递机制提供了依据。

2. **文献名称**:*"Substance P antibody-based ELISA for quantitative analysis in inflammatory models"*

**作者**:Bradesi, S. et al.

**摘要**:作者开发了一种基于Substance P抗体的ELISA检测方法,用于定量分析大鼠结肠炎模型中的Substance P浓度变化,发现其与炎症严重程度呈正相关,证实了抗体在体液检测中的可靠性。

3. **文献名称**:*"Role of Substance P in cutaneous inflammation: Antibody-mediated neutralization studies"*

**作者**:Steinhoff, M. et al.

**摘要**:研究利用Substance P抗体中和实验,证明该神经肽在银屑病样皮肤炎症中的关键作用,抗体通过阻断受体结合显著减轻了病理症状,提示其潜在治疗价值。

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如需进一步文献,建议通过PubMed或Google Scholar检索关键词“Substance P antibody”、“Substance P immunohistochemistry”等。

       

背景信息

Substance P antibody background:

Substance P is a neuropeptide belonging to the tachykinin family, primarily functioning as a neurotransmitter and neuromodulator. It binds to neurokinin-1 (NK-1) receptors and plays critical roles in pain signaling, inflammatory responses, mood regulation, and emesis. Antibodies targeting Substance P are essential tools for detecting and studying its distribution, expression, and function in biological systems. Developed through immunization protocols using synthetic Substance P or its fragments, these antibodies enable researchers to visualize the peptide in tissues (via immunohistochemistry), quantify its levels (using ELISA or radioimmunoassays), and explore its interactions with receptors (through blocking experiments).

Substance P antibodies are widely applied in neuroscience, immunology, and pharmacology research, particularly in studies of chronic pain, neurodegenerative diseases, and inflammatory conditions. However, their utility depends on specificity, as cross-reactivity with other tachykinins (e.g., neurokinin A) can occur due to structural similarities. Validation via knockout controls or mass spectrometry is often recommended. Monoclonal antibodies offer consistency, while polyclonal versions may detect multiple epitopes. Commercial availability since the late 20th century has accelerated research into Substance P's pathophysiological roles and therapeutic targeting, including investigational NK-1 receptor antagonists.

       
关键字: SubstanceP抗体;SubstanceP;SubstanceP Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

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