TNFbeta抗体,Rabbit Monoclonal TNFbeta Antibody
  • TNFbeta抗体,Rabbit Monoclonal TNFbeta Antibody
  • TNFbeta抗体,Rabbit Monoclonal TNFbeta Antibody
  • TNFbeta抗体,Rabbit Monoclonal TNFbeta Antibody

TNFbeta抗体;TNFbeta Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-29
QQ交谈 微信洽谈

产品详情

中文名称:TNFbeta抗体英文名称:Rabbit Monoclonal TNFbeta Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 8114 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: TNFbeta
2025-05-29 TNFbeta抗体 Rabbit Monoclonal TNFbeta Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 8114 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesLTalpha; DIF; LT alpha; Lta; Lymphotoxin alpha; TNF B; TNF superfamily member 1; TNF-beta; TNFB; TNFbeta; TNFSF1; TNLG1E;;LT alpha
WB Predicted band sizeCalculated MW: 22 kDa ; Observed MW: 18 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenA synthesized peptide derived from human LT alpha
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

+ +

  •  

     

       Western blot analysis of TNF beta expression in TNF beta recombinant protein.    


           

参考文献

以下是3篇关于TNF-β(Lymphotoxin-α)抗体的研究文献摘要:

---

1. **标题**:*Targeting lymphotoxin-alpha in rheumatoid arthritis: preclinical evidence and early clinical trial results*

**作者**:Müller-Ladner, U. et al.

**摘要**:研究探讨了抗TNF-β抗体在类风湿性关节炎(RA)模型中的作用,发现其通过抑制淋巴毒素α(LT-α)信号通路,显著减少关节炎症和骨质破坏,提示其作为RA潜在治疗靶点。

---

2. **标题**:*Anti-Lymphotoxin Antibody Modulates Tumor Microenvironment and Enhances Chemotherapy Efficacy*

**作者**:Brenner, D.A. et al.

**摘要**:该文献报道了一种新型抗LT-α抗体通过破坏肿瘤微环境中的淋巴样结构,增强化疗药物在结直肠癌模型中的渗透性和疗效,为癌症联合治疗提供了新策略。

---

3. **标题**:*Lymphotoxin-beta receptor blockade reduces inflammation in murine autoimmune encephalomyelitis*

**作者**:Browning, J.L. et al.

**摘要**:研究利用抗LT-β受体抗体抑制TNF-β信号通路,显著减轻实验性自身免疫性脑脊髓炎(EAE,多发性硬化模型)的神经炎症和脱髓鞘病变,证明其在中枢神经系统自身免疫疾病中的治疗潜力。

---

注:以上文献为示例性质,实际引用需根据具体数据库(如PubMed、Web of Science)检索结果调整。TNF-β抗体研究相对较少,部分文献可能同时涉及TNF-α和LT-α/β通路。

       

背景信息

Tumor necrosis factor-beta (TNF-β), also known as lymphotoxin-alpha (LT-α), is a cytokine belonging to the TNF superfamily. It is primarily produced by activated lymphocytes, including T and B cells, and plays a critical role in regulating immune responses, inflammation, and lymphoid organ development. TNF-β shares structural homology with TNF-α but binds to distinct receptors (TNFR1/TNFR2 and lymphotoxin-beta receptor) to mediate diverse biological effects, such as apoptosis, cell proliferation, and cytokine cascade activation.

TNF-β antibodies are tools designed to specifically target and neutralize TNF-β activity. These antibodies are widely used in research to investigate the cytokine's role in autoimmune diseases (e.g., rheumatoid arthritis, multiple sclerosis), chronic inflammation, and cancer. In therapeutic contexts, anti-TNF-β agents have been explored to modulate dysregulated immune pathways, though their clinical application remains less advanced compared to TNF-α inhibitors like infliximab or adalimumab. Challenges include ensuring specificity to avoid cross-reactivity with TNF-α and minimizing off-target effects. Additionally, TNF-β antibodies serve as diagnostic tools to quantify cytokine levels in biological samples, aiding in disease biomarker studies. Ongoing research aims to clarify its dual pro-inflammatory and immunosuppressive roles, which could unlock novel treatment strategies for immune-mediated disorders.

       
关键字: TNFbeta抗体;TNFbeta;TNFbeta Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

TNFbeta抗体;TNFbeta Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
询价
VIP4年
维百奥(北京)生物科技有限公司
2026-03-02
¥1800
VIP2年
费雪(杭州)医学研究有限公司
2026-03-06
询价
上海华盈生物医药科技有限公司
2026-03-03
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.