2-Oct抗体,Rabbit Monoclonal 2-Oct Antibody
  • 2-Oct抗体,Rabbit Monoclonal 2-Oct Antibody
  • 2-Oct抗体,Rabbit Monoclonal 2-Oct Antibody
  • 2-Oct抗体,Rabbit Monoclonal 2-Oct Antibody

2-Oct抗体;2-Oct Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-30
QQ交谈 微信洽谈

产品详情

中文名称:2-Oct抗体英文名称:Rabbit Monoclonal 2-Oct Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 8232 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: 2-Oct
2025-05-30 2-Oct抗体 Rabbit Monoclonal 2-Oct Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 8232 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF1/20-1/50 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC1/50-1/200 Human,Mouse,Rat
FCM1/20-1/100 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesNF A2; Oct 2; Oct-2; OTF-2; OTF2; POU2F2; ;45567
WB Predicted band sizeCalculated MW: 51 kDa ; Observed MW: 58 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat
ImmunogenA synthesized peptide derived from human Oct 2
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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       Western blot analysis of Oct-2 expression in Ramos cell lysate.    


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       All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    


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       All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    


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       All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.    


           

参考文献

以下是关于2-Oct(或Oct-2)抗体的虚构参考文献示例(仅供参考,非真实文献):

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1. **文献名称**: *Oct-2 regulates B cell-specific immunoglobulin gene expression*

**作者**: Smith, J., et al.

**摘要**: 研究探讨了转录因子Oct-2在B淋巴细胞中对免疫球蛋白基因的调控作用,利用Oct-2抗体进行染色质免疫沉淀(ChIP)实验,证实其直接结合于IgH基因增强子区域。

2. **文献名称**: *Role of Oct-2 in autoimmune disorders: Insights from antibody-mediated knockdown models*

**作者**: Lee, H., & Martinez, R.

**摘要**: 通过Oct-2抗体阻断实验,发现Oct-2在多发性硬化症患者B细胞中异常高表达,提示其可能通过调控炎症因子参与自身免疫反应。

3. **文献名称**: *Structural characterization of Oct-2 DNA-binding domain using monoclonal antibodies*

**作者**: Gupta, S., et al.

**摘要**: 报道了一种高特异性Oct-2单克隆抗体的开发,通过X射线晶体学揭示了Oct-2蛋白与DNA结合的分子机制,为靶向药物设计提供依据。

4. **文献名称**: *Oct-2 as a biomarker in lymphoma: Immunohistochemical analysis*

**作者**: Tanaka, K., et al.

**摘要**: 利用Oct-2抗体对淋巴瘤组织样本进行免疫组化分析,发现Oct-2高表达与B细胞淋巴瘤的恶性程度及预后不良显著相关。

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注:以上文献为示例性质,实际研究中请通过学术数据库(如PubMed)查询真实发表的论文。

       

背景信息

The 2-Oct antibody, often associated with the transcription factor Oct-2. is a protein of interest in molecular biology and immunology. Oct-2 belongs to the POU (Pit-Oct-Unc) domain family of transcription factors, which regulate gene expression by binding to specific DNA sequences. Oct-2 is predominantly expressed in B lymphocytes and neuronal cells, where it plays a critical role in B-cell development, differentiation, and immunoglobulin gene regulation. Its interaction with coactivators like BOB.1 (OBF-1) enhances transcriptional activation, particularly at immunoglobulin promoters, making it essential for adaptive immunity.

In research, the 2-Oct antibody is widely used to detect Oct-2 protein levels in experimental models, aiding studies on B-cell malignancies, autoimmune disorders, and neurological diseases. Aberrant Oct-2 expression has been linked to conditions such as systemic lupus erythematosus (SLE) and certain B-cell lymphomas. The antibody’s applications include Western blotting, immunohistochemistry, and flow cytometry, providing insights into cellular localization and expression dynamics. Additionally, Oct-2’s role in neuronal gene regulation has spurred investigations into neurodegenerative diseases. Despite its specificity, cross-reactivity with related POU proteins (e.g., Oct-1) requires careful validation. Overall, the 2-Oct antibody remains a vital tool for dissecting transcriptional mechanisms in immunity and neurobiology.

       
关键字: 2-Oct抗体;2-Oct;2-Oct Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
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