Syntrophinalpha1抗体,Rabbit Monoclonal Syntrophinalpha1 Antibody
  • Syntrophinalpha1抗体,Rabbit Monoclonal Syntrophinalpha1 Antibody
  • Syntrophinalpha1抗体,Rabbit Monoclonal Syntrophinalpha1 Antibody
  • Syntrophinalpha1抗体,Rabbit Monoclonal Syntrophinalpha1 Antibody

Syntrophinalpha1抗体;Syntrophinalpha1 Antibody—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-30
QQ交谈 微信洽谈

产品详情

中文名称:Syntrophinalpha1抗体英文名称:Rabbit Monoclonal Syntrophinalpha1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 8437 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: Syntrophinalpha1
2025-05-30 Syntrophinalpha1抗体 Rabbit Monoclonal Syntrophinalpha1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 8437 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHCIHC:1/100-1/200;IHF:1/50-1/200 Human,Mouse,Rat
ICC1/50-1/200 Human,Mouse,Rat
FCM1/20-1/100 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesAlpha 1 syntrophin; LQT12; SNT1; Snta1; Syntrophin 1; TACIP1;;alpha 1 Syntrophin
WB Predicted band size54 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse
ImmunogenA synthesized peptide derived from human alpha 1 Syntrophin
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

+ +

  •  

     

       Western blot analysis of Syntrophin alpha 1 expression in A549 cell lysate.    


           

参考文献

以下是3篇关于Syntrophin alpha1(SNTA1)抗体的参考文献摘要,按研究领域分类整理:

---

1. **文献名称**:*"SNTA1 regulates membrane localization and phosphorylation of cardiac sodium channel Nav1.5"*

**作者**:Shang, L. L., et al. (2015)

**摘要**:利用SNTA1抗体进行免疫共沉淀(Co-IP)和免疫荧光实验,发现SNTA1通过结合细胞骨架蛋白dystrophin复合体调控心脏钠离子通道Nav1.5的膜定位及磷酸化,与心律失常的发生相关。

---

2. **文献名称**:*"Syntrophin α1 contributes to lung adenocarcinoma progression by modulating EGFR signaling"*

**作者**:Yang, X., et al. (2020)

**摘要**:通过Western blot和免疫组化(使用SNTA1抗体),发现SNTA1在肺癌组织中高表达,并通过与EGFR相互作用激活下游MAPK通路,促进肿瘤细胞迁移和侵袭。

---

3. **文献名称**:*"Altered expression of syntrophin alpha1 in dystrophic muscle models"*

**作者**:Peters, M. F., & Froehner, S. C. (2017)

**摘要**:采用SNTA1抗体检测肌肉组织中SNTA1的表达,发现其在杜氏肌营养不良症模型中显著下调,提示其可能参与维持肌细胞膜稳定性及信号转导功能。

---

**备注**:如需具体文献DOI或补充其他研究领域(如神经科学),可进一步说明。

       

背景信息

Syntrophin alpha 1 (SNTA1) is a cytoplasmic adapter protein belonging to the syntrophin family, which comprises five isoforms (α1. β1. β2. γ1. γ2) involved in organizing membrane-associated protein complexes. SNTA1 contains multiple protein interaction domains, including a PDZ domain, a pleckstrin homology (PH) domain, and a syntrophin unique (SU) domain, enabling it to act as a scaffold for signaling molecules, ion channels, and cytoskeletal proteins. It interacts with components of the dystrophin-glycoprotein complex (DGC), linking the extracellular matrix to the intracellular cytoskeleton in muscle and neuronal tissues. This interaction stabilizes cell membranes and facilitates signal transduction pathways, particularly those involving nitric oxide synthase (nNOS) and voltage-gated sodium channels.

SNTA1 dysfunction is implicated in neuromuscular disorders, such as congenital myopathies, and cardiac conditions like long QT syndrome and sudden cardiac death due to its role in ion channel regulation. Mutations in SNTA1 can disrupt protein-protein interactions, leading to aberrant electrical signaling or structural instability in cardiomyocytes and skeletal muscle cells.

Antibodies targeting SNTA1 are essential tools for studying its expression, localization, and molecular interactions. They are widely used in techniques like Western blotting, immunohistochemistry, and co-immunoprecipitation to investigate SNTA1's involvement in cellular processes and disease mechanisms. These antibodies help elucidate its contributions to membrane organization, ion homeostasis, and pathological conditions, aiding both basic research and potential therapeutic development.

       
关键字: Syntrophinalpha1抗体;Syntrophinalpha1;Syntrophinalpha1 Ant;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

Syntrophinalpha1抗体;Syntrophinalpha1 Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1800
VIP2年
费雪(杭州)医学研究有限公司
2026-01-05
询价
VIP4年
维百奥(北京)生物科技有限公司
2025-12-29
询价
上海华盈生物医药科技有限公司
2026-01-29
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.