RetinoicAcidReceptorbeta抗体,Rabbit Monoclonal RetinoicAcidReceptorbeta Antibody
  • RetinoicAcidReceptorbeta抗体,Rabbit Monoclonal RetinoicAcidReceptorbeta Antibody
  • RetinoicAcidReceptorbeta抗体,Rabbit Monoclonal RetinoicAcidReceptorbeta Antibody
  • RetinoicAcidReceptorbeta抗体,Rabbit Monoclonal RetinoicAcidReceptorbeta Antibody

RetinoicAcidReceptorbeta抗体;RetinoicAcidReceptorbeta Antibody—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-30
QQ交谈 微信洽谈

产品详情

中文名称:RetinoicAcidReceptorbeta抗体英文名称:Rabbit Monoclonal RetinoicAcidReceptorbeta Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 8476 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: RetinoicAcidReceptorbeta
2025-05-30 RetinoicAcidReceptorbeta抗体 Rabbit Monoclonal RetinoicAcidReceptorbeta Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 8476 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/1000-1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHCIHC:1/100-1/200;IHF:1/50-1/200 Human,Mouse,Rat
ICC1/50-1/200 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesHAP; NR1B2; RAR B; RAR beta; RAR epsilon; RARB; RRB2;;Retinoic acid receptor beta
WB Predicted band sizeCalculated MW: 50 kDa ; Observed MW: 55 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenA synthesized peptide derived from human Retinoic acid receptor beta
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

+ +

  •  

     

       Western blot analysis of Retinoic Acid Receptor beta expression in MCF7 cell lysate.    


  •  

     

       All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.    


           

参考文献

以下是3篇与Retinoic Acid Receptor β (RARβ)抗体相关的参考文献,按文献标题、作者及摘要内容简要概括:

---

1. **"Retinoic acid receptor β induces liver fibrosis injury by modulating mitochondrial calcium uptake"**

*Authors: Li, X., Zhang, Y., et al.*

**摘要**: 研究利用RARβ特异性抗体通过Western blot和免疫组化分析,证明RARβ通过调控线粒体钙离子摄取通路加重肝纤维化,抗体用于验证RARβ在肝组织中的表达水平变化。

---

2. **"Epigenetic silencing of RARβ in lung adenocarcinoma correlates with mutant EGFR signaling"**

*Authors: Kim, J.S., Park, S.M., et al.*

**摘要**: 通过RARβ抗体进行染色质免疫沉淀(ChIP)和免疫荧光实验,发现EGFR突变通过启动子甲基化抑制RARβ表达,抗体在表观遗传调控机制研究中发挥关键作用。

---

3. **"RARβ as a tumor suppressor in breast cancer: Antibody-based detection and therapeutic implications"**

*Authors: Hall, J.M., Greco, T.P., et al.*

**摘要**: 研究使用RARβ单克隆抗体分析乳腺癌组织样本,证实RARβ低表达与肿瘤侵袭性相关,抗体检测结果为预后评估提供潜在生物标志物。

---

注:以上文献名为示例性概括,实际引用时需根据具体研究补充完整信息及DOI号。建议通过PubMed或Web of Science以“RARβ antibody”及研究领域(如癌症、发育生物学)为关键词检索最新文献。

       

背景信息

The retinoic acid receptor beta (RARβ) is a nuclear receptor that plays a critical role in mediating the effects of retinoic acid (RA), a metabolite of vitamin A essential for cell differentiation, proliferation, and apoptosis. As part of the RAR subfamily (RARα, β, γ), RARβ binds to RA and forms heterodimers with retinoid X receptors (RXRs) to regulate the transcription of target genes by interacting with specific RA response elements (RAREs) in DNA. RARβ is particularly notable for its tumor-suppressive functions, as its expression is frequently downregulated in various cancers due to promoter hypermethylation or epigenetic silencing, making it a biomarker of interest in oncology research.

Antibodies targeting RARβ are vital tools for studying its expression, localization, and functional roles in both normal and pathological conditions. These antibodies enable techniques such as Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and chromatin immunoprecipitation (ChIP) to investigate RARβ protein levels, tissue distribution, and DNA-binding activity. Researchers also use RARβ antibodies to explore its involvement in developmental processes, cellular responses to RA therapy, and mechanisms underlying chemoprevention or resistance in cancers. Specific isoforms (e.g., RARβ1. β2. β4) may be distinguished using isoform-selective antibodies, aiding in dissecting their distinct biological roles. Validation of RARβ antibodies for specificity and cross-reactivity is crucial, given the structural similarities among nuclear receptor family members.

       
关键字: RetinoicAcidReceptor;RetinoicAcidReceptor;RetinoicAcidReceptor;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

RetinoicAcidReceptorbeta抗体;RetinoicAcidReceptorbeta Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1800
VIP2年
费雪(杭州)医学研究有限公司
2026-03-27
询价
VIP4年
维百奥(北京)生物科技有限公司
2026-03-02
询价
上海华盈生物医药科技有限公司
2026-03-19
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.