RibophorinI抗体,Rabbit Monoclonal RibophorinI Antibody
  • RibophorinI抗体,Rabbit Monoclonal RibophorinI Antibody
  • RibophorinI抗体,Rabbit Monoclonal RibophorinI Antibody
  • RibophorinI抗体,Rabbit Monoclonal RibophorinI Antibody

RibophorinI抗体;RibophorinI Antibody—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-30
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产品详情

中文名称:RibophorinI抗体英文名称:Rabbit Monoclonal RibophorinI Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 8612 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: RibophorinI
2025-05-30 RibophorinI抗体 Rabbit Monoclonal RibophorinI Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 8612 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/1000-1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHCIHC:1/100-1/200;IHF:1/50-1/200 Human,Mouse,Rat
ICC1/50-1/200 Human,Mouse,Rat
FCM1/20-1/100 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesOST1; RBPH1; Ribophorin I; Rpn1;;RPN1
WB Predicted band size69 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Rat
ImmunogenA synthesized peptide derived from human RPN1
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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       Western blot analysis of extracts from Hela cells, using Ribophorin I antibody.    


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       All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.    


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       All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.    


           

参考文献

以下是3篇关于Ribophorin I抗体的参考文献概览(虚构示例,供格式参考):

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1. **文献名称**: *Ribophorin I as a Novel Biomarker in Hepatocellular Carcinoma*

**作者**: Li, X. et al.

**摘要**: 研究利用Ribophorin I特异性抗体,通过免疫组化发现其在肝癌组织中高表达,并证实其与患者预后不良相关,提示其作为潜在诊断标志物的价值。

2. **文献名称**: *Role of Ribophorin I in ER-associated Protein Glycosylation*

**作者**: Müller, T. & Zimmermann, R.

**摘要**: 通过Western blot和免疫荧光技术,使用Ribophorin I抗体探究其在内质网中与OST复合物相互作用,揭示其在N-糖基化中的调控机制。

3. **文献名称**: *Antibody-based Screening of Ribophorin I in Multiple Myeloma*

**作者**: García-Sanz, A. et al.

**摘要**: 开发高特异性Ribophorin I单克隆抗体,用于多发性骨髓瘤患者样本检测,发现其表达水平与肿瘤侵袭性正相关,为靶向治疗提供依据。

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注:以上文献为示例,实际引用需查询真实数据库(如PubMed)。建议使用关键词“Ribophorin I antibody”结合研究领域筛选文献。

       

背景信息

Ribophorin I is a conserved transmembrane glycoprotein predominantly located in the rough endoplasmic reticulum (ER). It forms a heterodimeric complex with Ribophorin II, which is essential for the assembly and function of the oligosaccharyltransferase (OST) complex—a critical enzyme machinery mediating N-linked glycosylation. This post-translational modification involves the transfer of preassembled oligosaccharides to specific asparagine residues on nascent polypeptides, playing a vital role in protein folding, quality control, and cellular trafficking. Ribophorin I also interacts with ribosomes and Sec61 translocons, facilitating the coupling of protein translocation and glycosylation.

Antibodies targeting Ribophorin I are valuable tools for studying ER-associated processes, including glycoprotein biosynthesis, ER stress responses, and diseases linked to glycosylation defects. They are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to assess protein expression, localization, and molecular interactions. In cancer research, Ribophorin I antibodies have been employed to investigate its overexpression in certain malignancies, such as multiple myeloma, where it may serve as a potential biomarker. Additionally, these antibodies aid in exploring Ribophorin I's role in ER homeostasis and its implications in neurodegenerative disorders. Their specificity and reliability make them indispensable for elucidating the molecular mechanisms underlying protein maturation and ER-related pathologies.

       
关键字: RibophorinI抗体;RibophorinI;RibophorinI Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

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