Product Name：ARF(26–44), cell-permeable
CAS No.：935732-44-8
Synonyms：抗肿瘤肽ARF(26–44), cell-permeable
Catalog No.：220P061
Brand：Typeptide Biotech（肽研生物）
Description：ARF(26–44), cell-permeable是一种抗肿瘤肽，是由28个氨基酸组成的多肽，来源于 p14ARF 肿瘤抑制蛋白的特定氨基酸序列。ARF(26–44) cell-permeable 作为 FoxM1 (一种叉头框 M1 转录因子) 的功能抑制剂，在小鼠肝细胞癌 (HCC) 治疗中显示出了显著的抗肿瘤活性，能够显著增加肿瘤细胞的凋亡 (apoptosis) 以及减少肿瘤细胞增殖和血管生成。ARF(26–44), cell-permeable 可用于肿瘤治疗的研究。
ARF (26-44), cell competent, is an anti-tumor peptide composed of 28 amino acids derived from the specific amino acid sequence of p14ARF tumor suppressor protein. ARF (26-44) cell mature, as a functional inhibitor of FoxM1 (a transcription factor with a forked frame M1), has shown significant anti-tumor activity in the treatment of mouse hepatocellular carcinoma (HCC), significantly increasing tumor cell apoptosis and reducing tumor cell proliferation and angiogenesis. ARF (26-44), cell competent, can be used for research on tumor treatment.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | rrrrrrrrrKFVRSRRPRTASCALAFVN |
Sequence(3-letter code) | d{Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg}-Lys-Phe-Val-Arg-Ser-Arg-Arg-Pro-Arg-Thr-Ala-Ser-Cys-Ala-Leu-Ala-Phe-Val-Asn-OH |
Peptide Structure | 
|
Molecular Formula | C149H267N69O33S1 |
Molecular Weight | 3585.22 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： ARF(26–44), cell-per;抗肿瘤肽ARF(26–44), cell;935732-44-8;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。