Product Name:GAD65 (524-543)
CAS No.:152468-44-5
Synonyms:谷氨酸脱羧酶 65(524-543)
Catalog No.:220P094
Brand:Typeptide Biotech(肽研生物)
Description:GAD65 (524-543)是谷氨酸脱羧酶 65 (GAD65) 的氨基酸 524 至 543 片段。GAD65 (524-543)是该胰岛抗原的首批片段之一,可在自发性自身免疫性糖尿病的非肥胖糖尿病 (NOD) 小鼠模型中诱导增殖性 T 细胞反应。该肽是对自发产生的糖尿病 T 细胞克隆 BDC2.5 的特异性刺激,可能亲和力较低。 p524-543 免疫增加了 NOD 小鼠对 BDC2.5 T 细胞过继转移诱导的 1 型糖尿病的易感性。
GAD65 (524-543) is the amino acid 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). GAD65 (524-543) is one of the first fragments of this islet antigen, which can induce proliferative T cell response in the non obese diabetes (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific stimulus to spontaneously generated diabetes T cell clone BDC2.5, and may have low affinity. Immunization with p524-543 increased the susceptibility of NOD mice to type 1 diabetes induced by adoptive transfer of BDC2.5 T cells.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | SRLSKVAPVIKARMMEYGTT |
Sequence(3-letter code) | H-Ser-Arg-Leu-Ser-Lys-Val-Ala-Pro-Val-Ile-Lys-Ala-Arg-Met-Met-Glu-Tyr-Gly-Thr-Thr-OH |
Peptide Structure | 
|
Molecular Formula | C97H168N28O28S2 |
Molecular Weight | 2238.67 |
订购联系方式:
南京肽研生物生物科技有限公司
手机号:19961912513(微信同号)
QQ: 2178255659
邮箱:sales@typeptide.com
联系人:顾经理
申明:本产品仅供科研使用,不得用于人体。
关键字: GAD65 (524-543);谷氨酸脱羧酶 65(524-543);152468-44-5;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园,是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神,持续投入研发,不断创新,致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。