Derived from a 50 year old Japanese male with generalised lymphadenopathy and heptosplenomegaly (Adult T-cell Leukaemia) by co-culture of his peripheral leukocytes with male umbilical cord lymphocytes. The cells carry HTLV-1 and support the growth of HIV. The cells should be handled under laboratory containment level 3 conditions.
标题:An acquired phosphatidylinositol 4-phosphate transport initiates T-cell deterioration and leukemogenesis
作者:Wenbin Zhong, Weize Lin, Yingjie Yang
杂志名称:Nature Communications
doi:10.1038/s41467-022-32104-7,IF:16.6
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