产品概述
MLKL (5E3) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
IHC-P
Human
产品性能
Unconjugated
Unmodified
IgG1
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
MLKL
197259
Q8NB16
产品应用
IHC: 1:50-1:100
-
研究背景
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
研究领域
Signal Transduction
武汉恩玑生命科技有限公司
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