产品概述
HDAC4 (4A3) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB,IP
Human,Mouse,Rat,Monkey
产品性能
Unconjugated
Unmodified
IgG2a
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
HDAC4
EC 3.5.1.98; HA6116; HD 4; HD4; HDAC 4; HDAC A; HDAC4; HDAC4_HUMAN; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288.
9759
P56524
产品应用
WB: 1:500-1:1000 IP: 1:20
Calculated MW: 119 kDa; Observed MW: 140 kDa
研究背景
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
研究领域
Epigenetics and Nuclear Signaling
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