产品概述
SIRT1 (2G10) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB,IP
Human
产品性能
Unconjugated
Unmodified
IgG2b
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
SIRT1
SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2
23411
Q96EB6
产品应用
WB: 1:500-1:1000 IP: 1:20
Calculated MW: 82 kDa; Observed MW: 120 kDa
研究背景
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.
研究领域
Cell Biology
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