产品概述
PARP1 (10C2) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB,IHC-P
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG1
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Ascitic Fluid
免疫原
PARP1
PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
142
P09874
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100
Calculated MW: 113 kDa; Observed MW: 116 kDa
研究背景
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
研究领域
Epigenetics and Nuclear Signaling
武汉恩玑生命科技有限公司
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