产品概述
SIRT6 (6C9) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB,ICC/IF,IP
Human,Mouse,Rat,Monkey
产品性能
Unconjugated
Unmodified
IgG1
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
SIRT6
2810449N18Rik; AI043036; Mono ADP ribosyltransferase sirtuin 6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; Regulatory protein SIR2 homolog; SIR2 like 6; SIR2 like protein 6; Sir2 related protein type 6; SIR2-like protein 6; SIR2
51548
Q8N6T7
产品应用
WB: 1:500-1:1000 IF: 1:50-1:200 IP: 1:20
Calculated MW: 39 kDa; Observed MW: 42 kDa
研究背景
The Silent Information Regulator (Sir2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as class III histone deacetylases. SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway.
研究领域
Epigenetics and Nuclear Signaling
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