产品概述
MGMT Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,IHC-P
Human
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
MGMT
Methylated-DNA--protein-cysteine methyltransferase
4255
P16455
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100
Calculated MW: 22 kDa; Observed MW: 22 kDa
研究背景
MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O(6) position of guanine, restoring guanine to its normal form without causing DNA breaks. MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents.
研究领域
Epigenetics and Nuclear Signaling
武汉恩玑生命科技有限公司
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