产品概述
Thrombomodulin Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,ICC/IF,IP
Human
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
THBD
CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM
7056
P07204
产品应用
WB: 1:500-1:1000 IF: 1:50-1:200 IP: 1:20
Calculated MW: 60 kDa; Observed MW: 95 kDa
研究背景
Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
研究领域
Cardiovascular
武汉恩玑生命科技有限公司
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