产品概述
Aprataxin Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,ICC/IF
Human
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
APTX
AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT
54840
Q7Z2E3
产品应用
WB: 1:500-1:1000 IF: 1:50-1:200
Calculated MW: 41 kDa; Observed MW: 41 kDa
研究背景
DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair (PubMed:15380105, PubMed:15044383, PubMed:16964241, PubMed:17276982, PubMed:24362567). Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species (PubMed:16964241, PubMed:24362567). Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (PubMed:16964241, PubMed:17276982, PubMed:24362567). Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH2) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (PubMed:16547001). Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) .
研究领域
Epigenetics and Nuclear Signaling
武汉恩玑生命科技有限公司
联系商家时请提及chemicalbook,有助于交易顺利完成!
在线客服