产品概述
Axin 2 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
AXIN2
Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin
8313
Q9Y2T1
产品应用
WB: 1:500-1:1000
Calculated MW: 94 kDa; Observed MW: 94 kDa
研究背景
Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.
研究领域
Cell Biology
武汉恩玑生命科技有限公司
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