产品概述
FOXO4 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,IP
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
FOXO4
FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1
4303
P98177
产品应用
WB: 1:500-1:1000 IP: 1:20
Calculated MW: 54 kDa; Observed MW: 65 kDa
研究背景
The Forkhead family of transcription factors is involved in tumorigenesis of rhabdomyosarcoma and acute leukemias. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
研究领域
Epigenetics and Nuclear Signaling
武汉恩玑生命科技有限公司
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