产品概述
Glutaminase Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,ICC/IF,IP
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
GLS
Glutaminase kidney isoform; GLS; GLS1; KGA; K-glutaminase; GAM; GAC; Glutaminase C; L-glutamine amidohydrolase
2744
O94925
产品应用
WB: 1:500-1:1000 IF: 1:50-1:200 IP: 1:20
Calculated MW: 73 kDa; Observed MW: 68 kDa
研究背景
Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. Isoform 1 and isoform 3 are activated by phosphate. Inhibited by BPTES. BPTES binds between subunits and favors dissociation of the tetramer into dimers.
研究领域
Neuroscience
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