产品概述
RNA Polymerases I/II/III Subunit ABC1 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,IHC-P
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
POLR2E
RPB5; XAP4; RPABC1; hRPB25; hsRPB5
5434
P19388
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100
Calculated MW: 25 kDa; Observed MW: 25 kDa
研究背景
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process .
研究领域
Epigenetics and Nuclear Signaling
武汉恩玑生命科技有限公司
联系商家时请提及chemicalbook,有助于交易顺利完成!
在线客服