产品概述
Superoxide Dismutase 1 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB
Human
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
SOD1
SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1
6647
P00441
产品应用
WB: 1:500-1:1000
Calculated MW: 16 kDa; Observed MW: 16 kDa
研究背景
SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.
研究领域
Signal Transduction
武汉恩玑生命科技有限公司
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