产品概述
XIAP Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
Xiap
API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3
11798
Q60989
产品应用
WB: 1:500-1:1000
Calculated MW: 56 kDa; Observed MW: 53 kDa
研究背景
Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state.
研究领域
Cell Biology
武汉恩玑生命科技有限公司
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