产品概述
Keap1 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,IHC-P
Human,Mouse
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
KEAP1
INrf2; KLHL19
9817
Q14145
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100
Calculated MW: 70 kDa; Observed MW: 60-64 kDa
研究背景
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
研究领域
Epigenetics and Nuclear Signaling
武汉恩玑生命科技有限公司
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