产品概述
RIP Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,ICC/IF,FC,IP
Mouse
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Affinity Purification
免疫原
Ripk1
Ripk1,Rinp,Rip,Rinp, Rip,Receptor-interacting serine/threonine-protein kinase 1,Cell death protein RIP,Receptor-interacting protein 1
19766
Q60855
产品应用
WB: 1:500-1:1000 IF: 1:50-1:200 IP: 1:20 FC: 1:50-1:100
Calculated MW:75 kDa;Observed MW: 75 kDa
研究背景
Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade (By similarity).Required for ZBP1-induced NF-kappa-B activation in response to DNA damage (PubMed:12654725, PubMed:19590578).
研究领域
Cell Biology
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