产品概述
Munc 13-4 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,FC
Human, Mouse
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Affinity Purification
免疫原
UNC13D
Munc13-4,Protein unc-13 homolog D
201294
Q70J99
产品应用
WB: 1:500-1:1000 FC: 1:50-1:100
Calculated MW:123 kDa;Observed MW: 123 kDa
研究背景
Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca2+-dependent secretory lysosome exocytosis in mast cells.
研究领域
Immunology
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