产品概述
HMGB1 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB,IHC-F,IHC-P,FC
Human, Mouse, Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Affinity Purification
免疫原
HMGB1
HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
3146
P09429
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100 FC: 1:50-1:100
Calculated MW:25 kDa;Observed MW: 29 kDa
研究背景
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.
研究领域
Epigenetics and Nuclear Signaling
武汉恩玑生命科技有限公司
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