产品概述
GSK3 alpha/beta Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB
Human,Rat,Hamster
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
GSK3A
Serine/threonine-protein kinase GSK3A
2931
P49840
产品应用
WB: 1:500-1:1000
Calculated MW: 51 kDa; Observed MW: 51,47 kDa
研究背景
GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
研究领域
Neuroscience
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