产品概述
Phospho-CDC37 (S13) (15P11) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB
Human,Mouse,Rat
产品性能
Unconjugated
Phospho Antibody
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Affinity purification
免疫原
CDC37
CC37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co-chaperone Cdc37;
11140
Q16543
产品应用
WB 1:1000-1:5000
45kDa
研究背景
CDC37 is an important component of the HSP90 chaperone complex. It was initially identified for its involvement in cell-cycle progression and was later found to have a much broader role as a chaperone for a wide variety of kinases and other proteins. CDC37 protein has an amino-terminal kinase binding domain followed by a central HSP90 binding domain. Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (PubMed:8666233). Inhibits HSP90AA1 ATPase activity (PubMed:23569206).
研究领域
武汉恩玑生命科技有限公司
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