产品概述
Phospho-ErbB3 (Y1222) (11E17) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB
Human
产品性能
Unconjugated
Phospho Antibody
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Affinity purification
免疫原
ERBB3
ERBB3; HER3; LCCS2; p180 ErbB3; p45 sErbB3; p85 sErbB3;
2065
P21860
产品应用
WB 1:1000-1:5000
148kDa
研究背景
Binds and is activated by neuregulins and NTAK. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134). Involved in the regulation of myeloid cell differentiation (PubMed:27416908).
研究领域
武汉恩玑生命科技有限公司
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