产品概述
Phospho-p53 (T55) (15G3) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB
Human
产品性能
Unconjugated
Phospho Antibody
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Affinity purification
免疫原
0
Antigen NY-CO-13; TP53; Tumor suppressor p53; Cellular tumor antigen p53; Phosphoprotein p53
P04637
产品应用
WB 1:1000
53kDa
研究背景
Plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.
研究领域
武汉恩玑生命科技有限公司
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