产品概述
Apg12 (18O8) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB,IHC-P,ICC/IF,IF-P
Human
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Affinity purification
免疫原
ATG12
APG12-like; APG12L; ATG12; Autophagy 12; FBR93; HAPG12;
9140
O94817
产品应用
WB 1:1000-1:5000, IHC-P/IF-P 1:50-1:200, ICC/IF 1:50-1:200
15kDa
研究背景
Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5. Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.
研究领域
武汉恩玑生命科技有限公司
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