产品概述
Caspase-7 (17N18) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB,IHC-P,FC,IF-P
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Affinity purification
免疫原
0
CMH-1; ICE-LAP3; MCH3; CASP7; Caspase-7; Caspase7;
P97864(mouse)(human:P55210 )
产品应用
WB 1:1000, IHC-P/IF-P 1:200-1:2000, FCM 1:20-1:50
34kDa
研究背景
Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis. Caspase-7 is an effector caspase (along with caspase-2 and -3), meaning that it cleaves essential cellular machinery rather than activating other caspases. Caspase-7 is cleaved by many enzymes, including caspases-3, -6, -8, -9 and granzyme B. Once activated, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase, or PARP.
研究领域
武汉恩玑生命科技有限公司
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