产品概述
Cyclin E2 (7T5) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB,IHC-P,ICC/IF,FC,IP,IF-P
Human
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Affinity purification
免疫原
CCNE2
CGE2; CYCE2; cyclin E2; G1/S-Specific cyclin E2;
9134
O96020
产品应用
WB 1:1000-1:5000, IHC-P/IF-P 1:50-1:200, ICC/IF 1:20-1:50, FCM 1:50, IP 1:20
47kDa
研究背景
The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Essential for the control of the cell cycle at the late G1 and early S phase.
研究领域
武汉恩玑生命科技有限公司
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