产品概述
JAM1 (18L11) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB,ICC/IF,FC,IP
Human
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Affinity purification
免疫原
F11R
F11R;CD321;JAM;JAM-1;JAM-A;JAM1;JAMA;JCAM;KAT;PAM-1;Junction adhesion molecule 1;
50848
Q9Y624
产品应用
WB 1:1000, ICC/IF 1:20, FCM 1:50, IP 1:20
33kDa
研究背景
Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T- cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).
研究领域
武汉恩玑生命科技有限公司
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