产品概述
LYRIC (10G11) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB,IHC-P,ICC/IF,IF-P
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Affinity purification
免疫原
MTDH
3D3; 3D3/LYRIC; AEG1; Astrocyte elevated gene 1; LYRIC; LYRIC/3D3; Metadherin; MTDH; Protein LYRIC;
92140
Q86UE4
产品应用
WB 1:2000-1:10000, IHC-P/IF-P 1:50, ICC/IF 1:100
64kDa
研究背景
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
研究领域
武汉恩玑生命科技有限公司
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