产品概述
Mast Cell Tryptase (7Q2) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
IHC-P,IF-P
Human
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Affinity purification
免疫原
TPSAB1
TPS1; TPS2; TPSAB1; TPSB1; MCP 7 ; Mast cell protease 7; Tryptase alpha 1;
7177
Q15661
产品应用
IHC-P/IF-P 1:200-1:1000
31kDa
研究背景
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).
研究领域
武汉恩玑生命科技有限公司
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