产品概述
Rab4 (18S8) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB,ICC/IF,FC,IP
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Affinity purification
免疫原
RAB4A
Rab4 ; RAB4A; HRES 1 ;RAB4; Ras related protein Rab 4A;
5867
P20338
产品应用
WB 1:1000-1:5000, ICC/IF 1:200-1:1000, FCM 1:100-1:200, IP 1:10-1:100
24kDa
研究背景
The protein encoded by this gene belongs to the rab family. Rab4A protein is involved in the regulation of procathepsin L secretion, it was either inhibited by expression of a Rab4A dominant-negative mutant or increased by overexpression of the wild-type Rab4A in human melanoma cells. Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed:15907487, PubMed:16034420). Involved in protein transport (PubMed:29425100). Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (PubMed:29425100). Acts as a regulator of platelet alpha- granule release during activation and aggregation of platelets (By similarity).
研究领域
武汉恩玑生命科技有限公司
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