产品概述
Tyrosinase (8Z10) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB,IHC-P,ICC/IF,FC,IF-P
Human,Mouse
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Affinity purification
免疫原
TYR
ATN; CMM8; LB24 AB; SHEP3; SK29 AB; Tumor rejection antigen AB; TYR;
7299
P14679
产品应用
WB 1:1000-1:5000, IHC-P/IF-P 1:100-1:500, ICC/IF 1:50-1:100, FCM 1:20-1:50
60kDa
研究背景
Tyrosinase, found in the membrane of melanosomes, is a key enzyme in the biosynthesis of melanin pigments. It is a melanocyte differentiation antigen and is expressed in normal melanocytes and malignant melanomas. Tyrosinase is implicated to be an antigen target for melanoma vaccines. This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds (By similarity). Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine (By similarity). In addition to hydroxylating tyrosine to DOPA (3,4- dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA- quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone (By similarity).
研究领域
武汉恩玑生命科技有限公司
联系商家时请提及chemicalbook，有助于交易顺利完成！
在线客服