产品概述
Insulin Receptor β Rabbit Monoclonal antibody
Rabbit Monoclonal antibody
Rabbit
WB,IHC,IF,IP,ELISA
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG,Kappa
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Protein A
免疫原
INSR
Insulin receptor;IR;CD antigen CD220;[Cleaved into: Insulin receptor subunit alpha;Insulin receptor subunit beta]
3643
P06213
产品应用
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Calculated MW:95kD;Observed MW:95kD
研究背景
Cell localization:Membrane.This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],
研究领域
武汉恩玑生命科技有限公司
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