产品概述
Parkin Rabbit Monoclonal antibody
Rabbit Monoclonal antibody
Rabbit
WB,IF,IP,ELISA
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG,Kappa
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Protein A
免疫原
PARK2
PARK2;PRKN;E3 ubiquitin-protein ligase parkin;Parkinson juvenile disease protein 2;Parkinson disease protein 2
5071
O60260
产品应用
WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Calculated MW:52kD;Observed MW:52kD
研究背景
Cell localization:Cytoplasm.The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008],
研究领域
武汉恩玑生命科技有限公司
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