产品概述
NDUFA1 Rabbit Monoclonal antibody
Rabbit Monoclonal antibody
Rabbit
WB,IHC,IP
Human
产品性能
Unconjugated
Unmodified
IgG,Kappa
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Protein A
免疫原
NDUFA1
NDUFA1;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 ;Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit;
4694
O15239
产品应用
WB 1:1000-5000;IHC 1:100-300;IP 1:50-100
Calculated MW:;Observed MW:8kD
研究背景
Cell localization:Mitochondrion inner membrane; Single-pass membrane protein; Matrix side..The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008],
研究领域
武汉恩玑生命科技有限公司
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