产品概述
TGF β1/3 Rabbit Monoclonal antibody
Rabbit Monoclonal antibody
Rabbit
WB,IF,IP,ELISA
Human,Mouse,Rat,
产品性能
Unconjugated
Unmodified
IgG,Kappa
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Protein A
免疫原
TGFB1 TGFB3
Transforming growth factor beta-1 proprotein;Latency-associated peptide;LAP;Transforming growth factor beta-1;TGF-beta-1;Transforming growth factor beta-3 proprotein;Transforming growth factor beta-3;TGF-beta-3;
7040;7043
P01137;P10600
产品应用
IHC 1:1000-1:4000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Calculated MW:44kD;Observed MW:44kD,13kD
研究背景
Cell localization:Secreted.This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic
研究领域
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