产品概述
FOXO4 Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,ICC/IF,FC,IP
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Polyclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Affinity Chromatography
免疫原
FOXO4
FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1
4303
P98177
产品应用
WB: 1:500-1:1000 IF: 1:50-1:200 IP: 1:20 FC: 1:50-1:100
Calculated MW: 54 kDa; Observed MW: 65 kDa
研究背景
The Forkhead family of transcription factors is involved in tumorigenesis of rhabdomyosarcoma and acute leukemias. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
研究领域
Epigenetics and Nuclear Signaling
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