产品概述
Phospho-YAP (Ser127) Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,IHC-P,ICC/IF
Human,Mouse,Rat
产品性能
Unconjugated
Phosphorylated
IgG
Polyclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
YAP1
YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65
10413
P46937
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100 ICC: 1:100-1:200
Calculated MW: 54 kDa; Observed MW: 65 kDa
研究背景
YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
研究领域
Signal Transduction
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