产品概述
CD130 Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,IHC-P
Human,Mouse
产品性能
Unconjugated
Unmodified
IgG
Polyclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Affinity Purification
免疫原
IL6ST
Interleukin-6 receptor subunit beta ,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta, IL-6RB,CDw130
3572
P40189
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100
Calculated MW: 104 kDa; Observed MW: 130-140kDa
研究背景
The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.
研究领域
Cell Biology
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