产品概述
Acetyl-p53 (Lys370) Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,ICC/IF,IP
Human,Mouse,Rat
产品性能
Unconjugated
Acetylated
IgG
Polyclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Affinity Chromatography
免疫原
TP53
Antigen NY-CO-13; Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53
7157
P04637
产品应用
WB: 1:500-1:1000 IF: 1:50-1:200 IP: 1:20
Calculated MW: 44 kDa; Observed MW: 53 kDa
研究背景
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.
研究领域
Cell Biology
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