产品概述
Phospho-PDPK1 (Ser241) Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,IHC-P,ICC/IF
Human,Mouse,Rat
产品性能
Unconjugated
Phosphorylated
IgG
Polyclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
PDPK1
PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1
5170
O15530
产品应用
WB: 1:500-1:1000 IHC: 1:50-1:100 ICC: 1:100-1:200
Calculated MW: 63 kDa; Observed MW: 63 kDa
研究背景
Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways including the activation of Akt and the PKC isoenzymes p70 S6 kinase and RSK. Through its effects on these kinases, PDK1 is involved in the regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis.
研究领域
Signal Transduction
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