产品概述
SCG10 (phospho Ser73) Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
IHC-P,IF-P,IF-F,ICC/IF,ELISA
Human,Mouse,Rat
产品性能
Unconjugated
Phospho Antibody
IgG
Polyclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
STMN2
STMN2; SCG10; SCGN10; Stathmin-2; Superior cervical ganglion-10 protein; Protein SCG10
11075
Q93045
产品应用
IHC-P 1:100-1:300, ELISA 1:5000, IF-P/IF-F/ICC/IF 1:50-200
研究背景
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010],function:May play a role in neuronal differentiation, and in modulating membrane interaction with the cytoskeleton during neurite outgrowth.,PTM:Sumoylated.,similarity:Belongs to the stathmin family.,subcellular location:Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms.,tissue specificity:Neuron specific.,
研究领域
Regulation of Microtubule Dynamics
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