产品概述
CD300a Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
IHC-P,IF-P,IF-F,ICC/IF,ELISA
Human,Rat,Mouse
产品性能
Unconjugated
Unmodified
IgG
Polyclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
CD300A CMRF35H IGSF12 HSPC083
CMRF35-like molecule 8 (CLM-8;CD300 antigen-like family member A;CMRF-35-H9;CMRF35-H9;CMRF35-H;IRC1/IRC2;Immunoglobulin superfamily member 12;IgSF12;Inhibitory receptor protein 60;IRp60;NK inhibitory receptor;CD antigen CD300a)
11314
Q9UGN4
产品应用
IHC-P 1:50-200, ELISA 1:10000-20000, IF-P/IF-F/ICC/IF 1:50-200
研究背景
CD300a molecule(CD300A) Homo sapiens This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],function:Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.,PTM:Phosphorylated on tyrosine.,similarity:Belongs to the CD300 family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Upon tyrosine-phosphorylation, interacts with PTN6/SHP-1 and PTPN11/SHP-2 and INPP5D.,tissue specificity:Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.,
研究领域
武汉恩玑生命科技有限公司
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